[Peg K]

Sue H – I was hoping the CT Scan would provide more info. The vets also were able to look in his mouth while he was under and didn’t see anything worrisome. Maybe I just have to give him more time. Other than this issue, he has really bounced back from the surgery and I’m so grateful for that! I have a call in to my local vet so will ask about gabapentin as well. Thanks for the quick response!

[Serge Z]

Replying to Peg K’s question about how much time to see effect for her Standard Poodle. Our Lab has hip dysplasia which we’ve known about since she was two. When she was 7 she stopped jumping into the rear of our SUV and onto the bed. We got lightweight stairs and she used those for over a year. We had tried Rimadyl with no visible effect. Then our vet suggested we try Galliprant. She is 62# and we used 60mg once a day.
Fortunately no tummy side effects and without even being asked, after three weeks she began jumping into the SUV so we put the stairs away. Then we asked her to try the bed, which she did with ease, so we put those stairs away also.
She has been on Galliprant for about a year now (she’ll be nine next week) and she just flies into the car. The bed is higher, but after sizing it up she jumps right up. Oh, and we trim her nails on a window seat which is even higher and we had been lifting her up. No more…jumps up with ease!
So we think that three weeks might be the watershed. Also we have an almost five year old terrier with a pinched disk right near her tail. She got herself into real pain when trying to get out of something we had stupidly left in the back yard. Couldn’t use her back legs! The pain meds got her on her feet and she and Galliprant has kept her out of trouble ever since.

[Sue H]

I was thinking of my teeth and mouth and I have a sensitive nerve, which is sometimes aggravated, when I chew something too hard myself. Is not seen on x-ray, but when described to my dentist, he said this can happen, like a sinus area near the tooth.

My Candy who passed from nasal carcinoma that had metastasized to her bones in her skull, had some issues with her teeth before we discovered the cancer. She would also not eat crunchy things sometimes, and her breath became bad. She did have a tooth pulled and teeth cleaned. Once we put all the symptoms together, including her nosebleeds, there was not a lot to be done for her, as her x-rays indicated. Her cancer was so extensive, surgery was not an option. We kept her as comfortable as possible. I miss my girl.

I would ask about the gabapentin vs galliprant and feed your dog softer food items if that works out ok for him. You and your vet know his history better than I would, but just though to mention in case.

Wish you the best with him.

[Peg K]

Thanks everyone for your quick responses! I just spoke with my vet who also said that we should give it at least 10 days before deciding it isn’t working. After that, he also suggests Gabapentin, but I’ll wait a few more days with the Galliprant and see if it starts to take effect. I am also worried about a return of the cancer, but trying not to go there in my head! Just keeping a close eye on him and glad for every day that we have and that he doesn’t seem to be in constant pain. Thanks for all the good wishes, we will gladly accept them!!

[Patti F]

Hello I am new to this site but wanted to ask some advice on Galliprant.
A little history…
Rocky – 12 year old Aussie mix
Has small mass in his liver since 2013 – very little change
Had a cancerous tumor removed from his leg this past summer 2017
Has had extreme and fast muscle atrophy of his head since the surgery this summer
Has had numerous eye problems since his surgery – with possible mass behind one eye
Jaw pain – hard to complete a yawn and not barking anymore – possible diagnosis Masticatory Myositis
Developed Cushings after the surgery and is much better on Vetoryl now
Eating and drinking well
He takes Gabapentin as well for osteoarthritis

Want to basically do pain management for him. Have had him on 60 mg of Galliprant for about a week now and we have seen maybe a slight improvement. Does it take longer than this to see improvement?

[Sue H]

Hi Patty, sorry to hear that Rocky has ben so ill. My Crystal showed improvement in a week or so, she is also on gabapentin as well, so that coupled with the Galliprant seems to help her. She was having issues with atrophy in her back legs. I would ask about adding gabapentin (not expensive) and seeing if that helps. You can always discontinue if 7-10 days does not help him.

I hope Rocky will soon be feeling better.

[Madeline O]

It sounds like Galliprant is a good option. We just started our 12 year old yellow Lab on it yesterday. She had TPLO surgery in May 2016 and we’ve been giving her Adequan injections for about 8 months now. The injections were helping immensely until recent below zero temps prevented her from daily exercise outdoors and she began having pain again. Vet put her on Tramadol and Gabapenten but I don’t like how drugged they make her plus the fact that they do nothing for the inflammation. She had been on Carprofen prior to the knee surgery but that drug caused her liver enzymes to go WAY up & now she’s got a 3cm liver mass. Our Vet recommends blood work after two weeks on Galliprant to compare with the tests done prior to going on it. Fingers crossed this drug will help her.

• This reply was modified 6 years, 11 months ago by Madeline O. Reason: misspelled Galliprant

[Sue H]

Madeline, I hope the Galliprant works for your dog! I was able to cut the dose in half for Crystal once the inflammation for her went down. When she is having a rough time, I give her a whole tablet again for a week to 10 days (all discussed with our vet), until we can maintain her on the lowest dose. Hoping your dog is running around again like my Crystal does.

[Peg K]

I sure hope the Galliprant works for your girl Madeline! After discussion with my vet and the cancer surgeon, we took Simon off the Galliprant (though still taking Gabapentin) pending Masticatory Myositis bloodwork which, if positive, means he can’t have Galliprant in his system once we begin treatment. It’s probably a longshot but nothing seems to be helping him. He is still crying out frequently, and we aren’t able to find the reason for it. It’s a heartwrenching sound and I hate that we can’t figure this out. Just waiting for my vet’s office to open so I can get results of the bloodwork which came in late yesterday afternoon. If MM is not the diagnosis, I guess he’ll go back on the Galliprant, combined with Gabapentin. It’s strange, because aside from these painful yelps, he seems okay although somewhat lethargic probably due to the Gaba. Anyway, will keep fingers (and paws!) crossed for your girl to have success with the Galliprant!

[Deneen L]

Hello Wondering how long the GI upset lasted after your dogs were taken off Galliprant? My 12 1/2 year old lab has been on it for about 2 months. He started to have loose stools/diarrhea last week. I called the vet and we decided to stop the galliprant Friday. I had him on chicken/rice Friday and Saturday. On Sunday I started to slowly add dog food in. He woke me up in the middle of the night to go outside, stools were loose again. Was it too soon to start adding his kibble? He’s really never had any issues at all in his life, I’ve been extremely lucky, so I have on real experience with it. Thank you!

[anonymous]

At least a few days, a week, 10 days at the most. Call the vet if you don’t start to see improvement soon.
I’d keep him on the bland diet for at least a few days, then don’t be surprised if he’s a little constipated, it takes a while for his GI system to calm down.

[Deneen L]

Thank you anon! I suspected I rushed it a bit.

[anonymous]

Plus, your dog is a senior. Mine was too. It takes them a little longer.

[Sue H]

Their system does take some time to settle down. Feeding his food is fine. If still having loose stools, give your dog some pure pumpkin (Libby’s makes this in a can). A big teaspoon full with food should help. If he is not better in 4-5 days, speak with your vet. Be sure he is drinking water so he does not get dehydrated. Hope he is feeling better by now.

[Deneen L]

Thank you! Unfortunately there’s been no change. He’s woke me up the past 2 nights around 3AM having to go and my son just called he had an accident in the house, which he never does. I thought the bland diet would help a bit but it doesn’t seem to be helping at all. I called the vet, waiting to hear back. UGH he was doing so well on the galliprant too, of corse now I’m not even sure that is the issue.

• This reply was modified 6 years, 10 months ago by Deneen L.

[Jamie W]

When my dog first went in galliprant over a year ago This happened to him too- never had issues and then suddenly pooping in the house- my vet had us take him off then galliprant until he had normal bowel movements for at least a few days and then reintroduce it. We skipped one daily dose a week wnd then any time he gets soft stool we skip a dose.
We did bland diet chicken, rice, pumpkin and the vet prescribed some meds- can’t rmemener what they are called but basically a Imodium For dogs. It did the trick and no he’s great on galliprant a year later. It looks like this is very common scenario if you read the thread! I hope it helps!

[Deneen L]

Jamie – I’m glad your dog bounced back! I’m hoping the vet tells me to give him pepto or something. Did you mix, chicken, rice and pumpkin all together? I thought about doing that but didn’t want the addition of the pumpkin to make it even worse.

[Jamie W]

I just did about a tablespoon of pumpkin in the food and if his bowel movements started to look orange I didn’t do pumpkin but it usually helps with the soft stools. I think I’ve seen at least 4 other people on here with pretty much exactly the same scenario/ for the first time in galliprant it upsets stomach and then once resolved works out well! I hope it works for you!

[anonymous]

If the vet suspects he’s dehydrated, he may want you to bring the dog in for subq fluids, this is not expensive and it will help big time.
I would keep the diet as simple as possible for now.
Less is more. Add water to meals. Do not give Pepto……….or anything else unless advised to do so by a vet that has examined the dog. No pumpkin, nothing.

[anonymous]

PS: Depending on how severe the symptoms are, you may want to consider going go the emergency vet, now.

[Sue H]

I have a Colie with a VERY sensitive stomach and he is not on Galliprant. The food that works best for him is Purina ONE SmartBlend True Instinct Grain Free Nutrient-Dense Nutrient Dense Formula Dry Dog Food. The only food that has NOT given him diarrhea. If he happens to eat some of one of my other dog’s food, then I give him a big teaspoon of pumpkin (this does not turn a dog’s stool orange that I have even known of, as it is a small amount). The fiber in the pumpkin is what helps curb the diarrhea. It may be that the bland diet is making him worse. There is a product called Purina Fortiflora Canine Nutritional Supplement (box can be bought on Amazon or from your vet) that restores the proper bacteria in your dog’s GI system, which may be out of whack from the diarrhea.)

I hope you have spoken with your vet and come up with a plan to help with the diarrhea. I know the feeling of being awakened at 3 am to let my Cody outside when he has to go, but better than cleaning him and diarrhea up inside….

Again, be sure your dg is drinking enough water, even if you take him out a few extra potty times, way worth this.

[Deneen L]

Thank everyone! I have spoken to my vet a few times. This AM he was put on Flagyl, fingers crossed. He went over 12 years without a single medication, barely ever an upset stomach that I can remember. Fingers crossed, I just want him to feel better, back to his normal self. I appreciate all the information on this topic, it helps to know we aren’t alone.

[Mike L]

Has anyone noticed any neurological effects from Galliprant? My 13-year-old Yorkie has an elevated liver count after being on Rimadyl, so new vet tried Galliprant. He seemed a little loopy. He’d stare at me at awkward times for no apparent reason. He’d get started for no apparent reason. I pulled him off 3 days ago, and so swear I’ve got my old Yorkie back. He never had problems with diarrhea. I’d like to be able to reduce any pain he may be feeling, but not at the expense of other issues.

• This reply was modified 6 years, 10 months ago by Mike L.
• This reply was modified 6 years, 10 months ago by Mike L. Reason: Trying to changed started to startled!

[zcRiley]

Previcox is THE best pain reliever. Given after a full meal. On others, my dog didn’t know who he was, where he was or who I was. Scared me to death.

[Scherry H]

Anybody notice sudden dog scooting after galliprant? My dog has never done this. Is this a sign of allergic reaction? His stool looks fine.

[anonymous]

Read the prior comments. Dogs scoot due to irritation, only a vet that examines the dog can determine the cause.

Get ready, loose stools are next, then diarrhea, then bloody diarrhea.

May want to put a call into the vet before the weekend, otherwise you may have to go to the emergency vet…if it is a adverse reaction to the galliprant.

[Sue H]

Scherry, I would call your vet. You and your vet know your dog best. How long has your dog been on Galliprant?

There are many reasons a dog will scoot. One of mine will if anything is on her ‘pants’ no matter how minor. She likes to be very, very clean.

anon101’s post sounded alarming to me. My dog has been on Galliprant for8-9 months now. We had some diarrhea in the beginning. Once her pain and walking issues resolved, I am able to use half the Galliprant dose and we have very occasional issues now with diarrhea.

[anonymous]

“anon101’s post sounded alarming to me. My dog has been on Galliprant for8-9 months now. We had some diarrhea in the beginning. Once her pain and walking issues resolved, I am able to use half the Galliprant dose and we have very occasional issues now with diarrhea.”

Did I criticize your post? No.

Every dog is different. Some dogs have sudden violent reactions to NSAIDS even if they have been stable on it for several months.

I saw it, close up and personal. Med had to be stopped immediately.

[anonymous]

“Scooting” is most often caused by anal gland impaction which can be caused by loose stools which can be caused by NSAIDS……..

[Sue H]

While there are occasions that warrant immediate vet care, I do not think alarming someone for a low incidence as a side effect of a medication, which the vet can explain, is the correct thing to do. The pet owner, the pet and the vet should make a decisions based on what the actual findings are, and what is best for the dog.

Medications do list ALL side effects, they have to by law. That does not mean that an instance of scooting will lead to “Get ready, loose stools are next, then diarrhea, then bloody diarrhea”, which you stated.

I am sorry if your dog experienced this first hand. It can happen, but the incidence is low.

[anonymous]

No one is here in a professional capacity.
See “commenting policy”

Therefore your opinion is no more valid than mine.

Pfft

PS: You are incorrect. Many dogs cannot tolerate NSAIDS. The incidence of side effects are not low.

[Scherry H]

Thanks to all who responded! I didn’t want to write a novel here about my dog’s history but anon 101 is correct. My dog is on his last try with NSAIDS due to intolerance. All was well for a few days with galliprant now all of the sudden I have I scooter. My boy is ten I know everything about him down to how many times his heart beats per minute. Lol. Not really but sort of. That is why the sudden scoot is significant! And no the vets are not the best at discussing these things objectively for whatever reason, that is why I came here with my question. I had read the entire thread thoroughly before I even started the galliprant a few days ago. There was one comment about scooting and I remembered it but couldn’t relocate it. I feel like real opinions from real case studies from dog owners and their pets have way more value than any vet I have ever had. So again, I am so grateful for all of you. A healthy dog can end up in ER within hours from NSAIDS, look it up. It’s true. Thanks anon101 !

[anonymous]

You’re welcome.

I hope your dog is okay. Just keep an eye on him for adverse reactions. Good luck.

[Scherry H]

Well it has been a bumpy ride for us and his arthritis since his diagnosis September 2017. We tried all NASAIDS horrible results and then tried Adequan injections biweekly until now. They were a miracle treatment until just recently which is why we are trying Galliprant. I asked his vet today about the scooting and he is not concerned. They never are until it’s too late. He wasn’t concerned when he vomitted the Novox and Deramax either until he was covered in red itchy bumps, by then we were in crisis mode. So that I s why I visit forums such as these and take my vets advice with a grain of salt. I am taking him off the galliprant and checking into Platlet Rich Plasma therapy with and acupuncture, fingers crossed. He is my whole world!!! Thanks again for everyone’s concern.

[Sue H]

Scherry, I hope he is doing better. My dog is also on gabapentin. Not sure if this is something your dog can take or tolerate well.

Are you able to get another vet to see your dog for another opinion? Sometimes this does help with reviewing options and deciding on the proper care for your dog.

[Scherry H]

Hi Sue! He seems good today. Tenchu has been on gabapentin since September 2017. I believe that it helps a lot He is able to rest better since he started it. We have seen many vets. We live in a nice city with lots of options. He has 3 now. Their opinions do differ a little at times. His homeopath over sees all decisions made by the allopathic doctors. I think with arthritis one just has to try everything and hope for the best. It’s just part of aging unfortunately. We haven’t tried acupuncture, PRP, cold laser, or chiropractic care yet, so they are next. That is one reason he has 3 vets and counting…..if I only I could find one practice that does it all. I do appreciate forums like this because I learn so much. Thank you!

[Sue H]

Scherry, awesome that you have the opportunity to have multi-vet input for him. I would love to hear about the platelet rich plasma therapy when he has that. I have had a similar type procedure for treatment of a different type of illness myself. They have since found that using these types of treatments can provide the benefit to a myriad of different medical conditions.

I hope something works for him. I have heard good things mostly regarding chiropractic and acupuncture for pets, too.

[Peg K]

Scherry – Years ago, I had a cat who lost movement in his back legs due to a spinal problem; my vet was also a specialist in Eastern medicines and gave him 3 rounds of acupuncture. He bounced right back, regained use of his back legs and I had him for another 3 years after that (he was 15 at the time). I am a firm believer in the power of acupuncture!! Would like to try it for my dog who is dealing with masticatory myositis and taking prednisone and gaba. Unfortunately there is no one nearby who specializes in acupuncture. Sending good vibes to you and Tenchu!

[Brenda F]

My dog Amber, now age 14, had PRP last year and it was not successful….after about 6 weeks the benefits of less stiffness and better mobility wore off. However, a few months later she had prp WITH stem cell and it was quite effective! She is coming up to one year now and there is still some benefit . Stem cell reduced the need for daily NSAIDS, so it was very helpful. Now we are back to fairly regular NSAID use as stem cell is wearing off , as it does between 9-12 months.

[Sue H]

Brenda, what is PRP? I am a believer in the proper use of stem cell treatment and I am glad this worked for your Amber!

[Donna R]

Mike L., You didn’t mention your Yorkie’s weight. If it’s less than eight pounds Galliprant can not be accurately dosed. It’s only recommended for dogs that are 8 pounds or more. Don’t know if that would be a symptom or not, since there is nothing stated in Manufacturers information provided with Galliprant. If your dog is on any other medications, it could be a drug incompatibility too.
Hopefully though your Vet would have caught any of those before prescribing it.

I’ve had my 50 lb 13yr old border collie chow mix on Galliprant for the last five months. She has severe hip dysplasia diagnosed when she was 10 months old and has degenerative arthritis in her hips, elbows and at least her right knee, which she had past corrective surgery on for a luxating patella that popped out of place and didn’t go back on it’s own. Her condition will only get worse, I’m under no illusion about this. The Galliprant helps her to remain mobile, for now at least and pretty much pain free. She also gets Gabapentin twice a day. In all other aspects of her health, she is doing very well for her age. She has had only slight gastric and bowel movement problems, which lasted only for a few days and was just soft to a little mushy stool, but not diarrhea. But as others have stated, she also was started on half a dose ( half of a 60 mg tablet), for about 10 days. Increased it by using a pill cutter to give an extra quarter of the pill for about another 10 days, then she got the whole dose. The soft stools happened about half way through the first increase and she’s been good since. She does get her blood work and urine tested also.
I know I’ll have to make that final decision in the near future as her hind legs are becoming weaker. I can’t exercise her much, we go for 10 to 15 minute slow walks. Sometimes just out the front door onto the lawn and back. I leave it up to her. I’d get her the underwater treadmill rehab, but she has a pressure sore that hasn’t completely healed yet and they won’t chance it due to possible infection. I’ve tried laser, helped some but got too expensive and the same with acupuncture. We are trying the Asissi Loop now. My dog has so many joints that need treatment though I don’t know how effective it will be and am trying to concentrate on the two or three worst areas.The Loop is expensive and is only prescribed by a Vet because it is an FDA cleared anti-inflamatory medical device. But the Loop is yours and treatments are done at home. I also massage her and use some acupressure on a few of the areas pressure points. Don’t know if it helps the condition so much as us just spending time together doing something she loves. Loves those rub downs. Just want her to be as comfortable as possible for as long as possible, knowing that I’ve tried all that I can for her.

[Sue H]

Donna, wish you the best for your girl.

[Scherry H]

Update on Tenchu Galliprant & PRP. Thank you for the remarks and suggestions. It has now been two weeks since his PRP injection. Sadly, it didn’t affect the left front paw which is the one he is noticeably lame in. They are suggesting a growth hormone injection next. They tell me that he probably won’t do well with stem cell therapy since their was no response from the PRP. I think we are going to move forward with acupuncture instead. He started having coughing hacking spells and some vomiting on even a quarter dose of galliprant so we are done with it too. His arthritis seems to be stable just with the gabeoentin and Adequan injections. We think he must have a torn ligament or something in that left leg. I will keep everyone posted about the acupuncture. Thanks to all who took the time to respond to my message! 💛

PRP stands for platelet rich plasma. It is a fairly easy technique no need for hospitalization if the injection is IV. If they need to inject into a joint, that is more complex and sedation is required. Tenchu had his done by IV since his X-ray didn’t show a need for a joint injection. It can be a very successful therapy for most dogs but they do not know why it helps some but not others. There are no side effects if done correctly.

[Brenda F]

My vet told me that they are discovering that the combination of prp with stem cell can be very helpful for some dogs, rather than prp alone. This was my dog’s case and she had no side effects. The procedure benefits began 2 months after, sometimes it is sooner or later, but I saw remarkable benefits for several months. I only wish it could work for longer rather than having to do the procedure every year.
I may give Galliprant another try but what I notice when Amber is on it is that it does not seem to last the full 24 hours like Metacam does and she gets stiff long before the next dose.

[John D. H]

Galliprant was prescribed to my Saint Bernard puppy for treating panosteitis. After about a week and a half he began to lessen his food intake. Three days later he hadn’t eaten in a day and a half. Rushed him to emergency vet. Stayed two days with interveinious feeding and pain med. After four days back on Galliprant he stopped eating again and rushed to regular vet for emergency surgery to relieve his blockage form his intestine. After returning home we started the Galliprant again and within 3 days he stopped eating again. 12 hours later he was dead. I never made the connection with the Galliprant neither did the vet.
Please if you use Galliprant carefully monitor your dogs eating and eliminating.

[Sue H]

John, I am so very, very sorry that you lost your Saint Bernard puppy. Thank you for sharing this sad post.

I have always monitored the intake and output of my dogs, as they eat different food for a reason and at times, may or may not be on a medication as well. I use different bowls and different colored bowls for each dog to prepare their meals and I also feed them separately so I can be sure they are eating, and if they are not, monitoring why they are not eating and calling my vet.

[John D. H]

Thank you Sue
We are very sad and also upset.

[Sue H]

John, have you and your vet contacted the company to let hem know what happened to your dog? I would do so.

[ivy c]

Yes, you’ll be able to provide Tramadol to dogs provided there’s a legitimate prescription with the proper dose data. Dogs expertise painful health problem and conjointlyinjuries, necessitating the employment of the pain medication Tramadol. The opioid-like pain reliever is prescribed for dogs only the medication is taken into accountbecause the best suited one for pain relief.
Tramadol, conjointly on the market in brand Ultram, is also used preponderantly in humans however constant came be employed in dogs further. Of course, the medication ought to be within the right dose strength. like humans, the employment of Tramadol in dogs ought to be through with the suitable precautions when consulting with the doctor. If administered right, Tramadol may be terribly helpful in managing the health problem or recovery of the dog.

When is Tramadol administered to dogs?

Tramadol is employed in dogs for pain relief almost like the means it’s in humans. The drug will facilitate manage conditions like cancer treatment connected pain, degenerative joint disease and different chronic sicknesses, chronic pain, and post-surgery. The dose is calculated per the load of the dog and adjusted reckoning on the dog’s response to the medication. Multiple doses is also administered in an exceedingly day, and it should take a couple of days to visualize improvement within the pain symptoms.

What ought to i do know before giving Tramadol to my dog?

Tramadol for dogs ought to lean within the right means for the foremost effective results. aspect effects will occur similar that experienced by humans. Drug dose also canbe cyanogenic for the dog. it’s suggested to stay track of the doses administered. Dogs area unit sometimes prescribed to require immediate unharness Tramadol pill. The extended unharness version isn’t suggested because the capsule is also chewed or broken the mouth itself, and also the effects will raise the danger of aspect effects.

Another word of caution is that the Tramadol utilized by humans might not be appropriate for the dog. parenthetically, individuals can purchase Tramadol and use it together with another pain relieving drug which will not be appropriate for dogs. Administering this medication may be harmful and you must perpetually discuss with the doctor for any Tramadol dose or name whole alterations.

What is the most effective thanks to provide Tramadol to my dog?

Dogs may be quite clever in avoiding swallowing the medication. The pet owner will insert the Tramadol pill within a scoop of food and build the dog swallow it simply. Else, the mouth of the dog ought to be command open gently and also the Tramadol pill pushed down the throat in order that it’s to be enveloped. For quicker pain relief, Tramadol injections or IV works best and also the doctor will administer the pain medication for your dog.

[Karen D]

Recent research has shown us that tramadol doesn’t work nearly as well in dogs as it does in people, because dogs lack the pain receptor that it targets. … It makes them sleepy while not actually making them less painful.
Tramadol is an opioid—essentially a synthetic version of morphine—and its painkilling effects in people depend largely on its conversion in the body to a substance called M1. But dogs don’t seem to convert tramadol to M1 as well as humans.

[Author]

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