Hi Cameron M, my vet doesn’t recommend Bravecto especially when you have elderly dog or a dog with health problems….. Bravecto doesn’t just leave the dogs system after 3 months, in Australia some vets are seeing too many side effects & recommending to give dose every 4 months, or just the once for the Summer months, ticks are still being found dead after 5 months after taking just 1 Bravecto chew dose…
*Bravecto stays in the body way tooo long, I wonder, dogs that are given Bravecto in 5 yrs what health problems will these poor dogs have or what health problems they will be dying from??
Found this when I googled Bravecto so I copied & paste….
Susana Wahs shared a link to the group: “Does Bravecto Kill Dogs”?
Long term side effects. Still finding dead ticks months after last dose ? Some disturbing facts I have found as to why.
I was researching as to why my dog has had 10 months of lack of appetite following his last dose of Bravecto, my vet came up with all the usual excuses, it is summer, it is warm, dogs eat less in summer, i told them it is Bravecto, my dog was 5 he has always eaten in summer, the house has air conditioning, he lives inside. This lack of appetite carried on through the winter, a full 10 months of putting his meal out for him at 9 am and him not touching it until 9 pm if he bothered at all some days, he always ate two meals a day 12 hours apart before he had his serious adverse reaction to Bravecto. Many days i have had to feed him by hand to encourage him to eat something.
I was also looking into why at 6 months after his last dose i found Dead attached ticks on his stomach, even though he was not taking any tick and flea treatment, then this April, i found 2 more dead attached ticks on him, 12 months after his last dose, I check him daily for ticks and fleas. Many other people have reported still finding dead attached ticks on their dogs upto a year after the last dose, i wanted to know how it could be and how long can this carry on for ?
So i started researching to see what the levels of Fluralaner are in the dogs plasma. I found some of the trials which mention the dogs had blood drawn to measure the levels, Fluralaner was quantifiable in plasma for up to 112 days after single oral dose ( they have not published any testing for levels of fluralaner after day 112 for us that are in Countries where we should give Bravecto every 3 months/ 90 days) so from this we know Bravecto is still efficient enough and quantifiable in the plasma to be still killing upto 112 days.
So then i start to look into the Bravecto Australia, which must be the same ingredients as they refer to the testing trials the same, the only additional testing carried out for its use in Australia was how effective it is against Paralysis ticks, which was an additional test to all the others we see. Australia is sold Bravecto that is to be taken every 4 months/ 120 days as it is still efficent to kill paralysis ticks for 4 months. Flualaner was quantifiable in plasma for up to 143 days after a single oral dose ( they have not published any testing for levels after the 143 days) Results: Fluralaner treatment efficacy against I. holocyclus was 100% at 72 h post treatment. Following re-infestations the efficacy remained at 100% at the 72 h assessments for 115 days and reached 95.7% at 143 days.
So still 100 per cent efficacy at 115 days ……… And still 95.7% at 143 days. ( Almost 5 months )
So what would the levels be at say 6 months, 7 months, 8 months, a year, 2 years ?
It does not just leave your dogs system at the 3 month marker, this is probably how we are seeing long term side effects. What have I done to my dog. He is still not fully recovered 15 months after his dose of Bravecto.
http://www.ncbi.nlm.nih.gov/pubmed/24606874
http://us.bravovets.com/published-studies-resources.aspx
http://www.bravecto.com.au/…/bravecto_technical_detailer.pdf
Pharmacokinetics of fluralaner in dogs following a single oral or intravenous administration. -…
Parasit Vectors. 2014 Mar 7;7:85. doi: 10.1186/1756-3305-7-85. Randomized Controlled Trial
NCBI.NLM.NIH.GOV|BY KILP S , ET AL.
Pharmacokinetics
